COMBINATION DEGRADABLE AND NON-DEGRADABLE MATRICES FOR ACTIVE AGENT DELIVERY

摘要

The present invention relates to combination degradable and no n- degradable matrices and related methods. In an embodiment, the invention includes an active agent delivery matrix including a degradable polymer netw ork, a non-degradable polymer network, the non-degradable polymer network in terspersed within the degradable polymer network, and an active agent. In an embodiment, the invention includes an active agent elution control matrix i ncluding a degradable polymer; and a non-degradable polymer interspersed wit h the degradable polymer. In an embodiment, the invention includes a method of making an active agent delivery matrix including mixing a degradable poly mer with a first solvent to form a degradable polymer solution; mixing a non -degradable polymer with a second solvent to form a non-degradable polymer s olution; and simultaneously depositing the degradable polymer solution and t he non-degradable polymer solution onto a substrate.