发明名称 Quinoxalinyl macrocyclic hepatitis C virus serine protease inhibitors
摘要 The present invention relates to compounds, including compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
申请公布号 AU2007265157(A1) 申请公布日期 2008.01.03
申请号 AU20070265157 申请日期 2007.06.26
申请人 ENANTA PHARMACEUTICALS, INC. 发明人 YAT SUN OR;YONGHUA GAI;GUOYOU XU;JOEL D. MOORE;DONG LIU;YING SUN;DEQIANG NIU;ZHE WANG;DATONG TANG
分类号 A61K31/4965;A61K31/498;A61K38/21;A61P31/12;C07D245/04 主分类号 A61K31/4965
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