CANCER THERAPY USING BcI-XL-SPECIFIC siNA

摘要

The invention relates to a double-stranded short interfering nucleic acid (siNA) molecule specific to the BcI-X_L transcript, comprising a sense and an antisense region, wherein the sense region comprises the nucleotide sequence SEQ ID NO: 1 or a sequence having at least 70 % identity, preferably at least 80 % identity, more preferably at least 90 % identity with said sequence, and the antisense region comprises a nucleotide sequence that is complementary to the sense region, and its use for treating cancer.