摘要 |
The present invention relates to combination degradable and non- degradable matrices and related methods. In an embodiment, the invention includes an active agent delivery matrix including a degradable polymer network, a non-degradable polymer network, the non-degradable polymer network interspersed within the degradable polymer network, and an active agent. In an embodiment, the invention includes an active agent elution control matrix including a degradable polymer; and a non-degradable polymer interspersed with the degradable polymer. In an embodiment, the invention includes a method of making an active agent delivery matrix including mixing a degradable polymer with a first solvent to form a degradable polymer solution; mixing a non-degradable polymer with a second solvent to form a non-degradable polymer solution; and simultaneously depositing the degradable polymer solution and the non-degradable polymer solution onto a substrate. |
申请人 |
SURMODICS, INC.;CHAPPA, RALPH, A.;HERGENROTHER, ROBERT, W.;BUSHENDORF, PAULA;SLAGER, JORAM |
发明人 |
CHAPPA, RALPH, A.;HERGENROTHER, ROBERT, W.;BUSHENDORF, PAULA;SLAGER, JORAM |