发明名称 |
METHOD FOR DISCRIMINATION OF METAPLASIAS FROM NEOPLASTIC OR PRENEOPLASTIC LESIONS |
摘要 |
<p>The present invention relates to a method for discrimination of p16<INK4a> overexpressing metaplasias from neoplastic or preneoplastic p16<INK4a> overexpressing lesions by determination of the level of high risk HPV encoded gene-products such as e.g. HPV E2 molecules in biological samples in the course of cytological testing procedures. The method thus enables for reduction of false positive results in the p16<INK4a> based detection of anogenital lesions in cytological testing procedures.</p> |
申请公布号 |
EP1493032(B1) |
申请公布日期 |
2008.01.02 |
申请号 |
EP20030758090 |
申请日期 |
2003.04.08 |
申请人 |
MTM LABORATORIES AG |
发明人 |
MARTIN, PETER;VON KNEBEL DOEBERITZ, MAGNUS |
分类号 |
G01N21/78;G01N33/574;C12N15/09;C12Q1/68 |
主分类号 |
G01N21/78 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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