NTRK1 GENETIC MARKERS ASSOCIATED WITH AGE OF ONSET OF ALZHEIMER'S DISEASE
摘要
<p>Haplotypes in the NTRK1 gene associated with age of onset of Alzheimer's Disease are disclosed. Compositions and methods for detecting and using these NTRK1 haplotypes in a variety of clinical applications are disclosed. Such applications include articles of manufacture comprising compounds effective in delaying the age of onset of AD in individuals at risk for developing AD and having one of these NTRK1 haplotypes, methods and kits for predicting the age of onset of AD in an individual at risk for developing AD based upon his/her haplotype profile, and methods for delaying the age of onset of AD in individuals at risk for developing AD based upon their haplotype profile.</p>
申请公布号
EP1678328(A4)
申请公布日期
2008.01.02
申请号
EP20040794919
申请日期
2004.10.14
申请人
PGXHEALTH, LLC
发明人
AERSSENS, JEROEN;ATHANASIOU, MARIA;BRAIN, CARLOS;COHEN, NADINE;DAIN, BRADLEY;DENTON, R., REX;JUDSON, RICHARD, S.;OZDEMIR, VURAL;REED, CAROL, R.