发明名称 |
Nucleoside and oligonucleotide analogues |
摘要 |
A probe for a gene or a primer for starting amplification comprising an oligonucleotide analogue comprising two or more nucleoside units, wherein at least one of the nucleoside units is a structure of the formula (2): wherein A represents a C<SUB>1</SUB>-C<SUB>4 </SUB>alkylene group, and B is an unsubstituted purin-9-yl group, an unsubstituted 2-oxo-pyrimidin-1-yl-group, a substituted purin-9-yl-group or a substituted 2-oxo-pyrimidin-1-yl group. Also a method for preventing or treating a disease preventable or treatable by the antisense or antigene activity of an oligonucleotide by administering the oligonucleotide analogue.
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申请公布号 |
US7314923(B2) |
申请公布日期 |
2008.01.01 |
申请号 |
US20030430705 |
申请日期 |
2003.05.05 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED;MITSUBISHI-KAGAKU FOODS CORPORATION |
发明人 |
KANEKO MASAKATSU;MORITA KOJI;IMANISHI TAKESHI |
分类号 |
C07H21/02;C12N15/09;A01N43/04;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7068;A61K31/7076;A61K31/7088;A61K31/712;A61K48/00;A61P31/12;A61P35/00;A61P43/00;C07H19/06;C07H19/067;C07H19/10;C07H19/16;C07H19/167;C07H19/20;C07H21/00;C07H21/04 |
主分类号 |
C07H21/02 |
代理机构 |
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代理人 |
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地址 |
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