| 发明名称 |
ANTIBODY VARIANTS AND FRAGMENTS THEREOF |
| 摘要 |
<p>A variant of a parent polypeptide comprising a human IgG Fc region is described, which variant has a better binding affinity for human C1q than the parent polypeptide and comprises an amino acid substitution in the IgG Fc region.</p> |
| 申请公布号 |
SI1068241(T1) |
申请公布日期 |
2007.12.31 |
| 申请号 |
SI19990030989T |
申请日期 |
1999.03.31 |
| 申请人 |
GENENTECH, INC. |
发明人 |
IDUSOGIE ESOHE EKINADUESE;MULKERRIN MICHAEL GEORGE;PRESTA LEONARD G.;SHIELDS ROBERT LAIRD |
| 分类号 |
G01N33/50;A61K38/00;A61K47/48;C07K16/18;C07K16/22;C07K16/28;C07K16/42;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/08;G01N33/15 |
主分类号 |
G01N33/50 |
| 代理机构 |
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