VACCINE FORMULATION POTENTIATED BY THE COMBINATION OF DNA AND AN ANTIGEN

摘要

THE INVENTION RELATES TO VACCINE ANTIGEN FORMULATION CONTAINING THE FOLLOWING MAIN COMPONENTS: A-) ONE OR MORE DNAS THAT EXPRESS ONE OR MORE PROTEINS IN THE IMMUNIZED INDIVIDUAL AND B-) A VIRAL ANTIGEN,IN SUITABLE PROPORTIONS.THE NOVELTY OF THE INVENTION LIES IN THE POTENTIATING EFFECT EXERTED BY AT LEAST ONE OF THE COMPONENTS ON THE IMMUNE RESPONSE GENERATED AGAINST THE OTHER.THE INVENTION ALSO RELATES TO THE DEVELOPMENT OF NOVEL FORMULATIONS,THAT MINIMIZE THE NUMBER OF COMPONENTS THAT CAN AMPLIFIED AND POTENTIATE THE RANGE OF IMMUNE RESPONSE AGAINTS DIFFERENT PATHOGEN ENTITIES.SAID FORMULATION ARE SUITABLE FOR USE IN THE PHARMACEUTICAL INDUSTRY FOR PROPHYLACTIC AND/OR THERAPEUTIC PURPOSE IN INDIVIDUALS.