| 摘要 |
The invention relates to a process for the synthesis of N-monosubstituted beta-amino alcohols of formula (I) and/or an addition salt of a proton acid, wherein Rand Rindependently represent Calkyl, Ccycloalkyl, phenyl, naphthyl, furanyl, benzofuranyl, thienyl, benzo [b] thienyl and aralkyl, wherein the alkyl moiety of the aralkyl residue is linear Calkyl, and the aryl moiety is selected from the group consisting of phenyl, naphthyl, furanyl, benzofuranyl, thienyl and benzo [b] thienyl, each aryl or aralkyl being optionally substituted with halogen, linear or branched Calkyl, linear or branched Calkoxy, Ccycloalkyl, CF, CF, OCFor OCF, via direct preparation of N-monosubstituted beta-amino ketones of said formula and its addition salts of proton acids, wherein Rand Rare as defined above. |
