发明名称 PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF MODAFINIL BY ASYMMETRIC OXIDATION
摘要 The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of : a) contacting a pro-chiral sulphide of formula (II) with a metal chiral complex, a base and an oxidizing agent in an organic solvent ; and optionally b) isolating the obtained sulphoxide of formula (I), wherein n, Y, R, R, Rand Rare as defined in claim 1.
申请公布号 EA009385(B1) 申请公布日期 2007.12.28
申请号 EA20060000593 申请日期 2004.09.17
申请人 CEPHALON FRANCE 发明人 REBIERE FRANCOIS;DIRET GERARD;PRAT LAURENCE
分类号 C07C315/02;C07C317/44;C07C327/28 主分类号 C07C315/02
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