LIVE TULAREMIC VACCINE NIK-SP.F. TULARENSIS

摘要

The invention relates medicine and veterinary science. The inventive live tularemic vaccine comprises Francisella tularensis NIK-sp strain which is deposited in the All-Rassian collection of industrial microorganisms FGUP GosNIIGenetica under index VKPM B-9311 and obtained by selecting according to a microbiological method from a pure line of R-form bacteria of a 15 NIIEG Francisella tularensis strain which is S-shaped with a maximum immunising dose for laboratory animals at a subcutaneous administration ranging from 1x10<SUP>4</SUP>to 1x10<SUP>8</SUP> of microbial cells and is capable to protect them against infection with Francisella tularensis subsp. tularensis 503.