发明名称 |
Pharmaceutical Compositions and Methods for Reducing Body Fat |
摘要 |
The invention concerns a method of reducing body fat content of a subject in need thereof, the method comprising administering to the subject an agent capable of down-regulating activity and/or expression of at least one component participating in protein digestion and/or absorption. Such agents may be (i) an oligonucleotide directed to an endogenous nucleic acid sequence expressing said at least one component participating in said protein digestion and/or absorption or (ii) a protease inhibitor directed to said at least one component participating in protein digestion and/or absorption. The invention is particularly directed to a method of reducing body fat content of a subject in need thereof, the method comprising administering to the subject serine protease inhibitor inhibiting both enteropeptidase and trypsin activity.
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申请公布号 |
US2007298025(A1) |
申请公布日期 |
2007.12.27 |
申请号 |
US20070748880 |
申请日期 |
2007.05.15 |
申请人 |
OBE THERAPY BIOTECHNOLOGY S.A.S. |
发明人 |
HAROSH ITZIK;FOURNES BENEDICTE;BARRADEAU SEBASTIEN |
分类号 |
A61K38/48;A61K36/00;A61P3/00 |
主分类号 |
A61K38/48 |
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