The present invention provides new methods for the assessment of cancer risk in the general population. These methods utilize particular alleles of selected genes, and particular combinations of genotypes, to identify individuals with increased or decreased risk of breast cancer. In addition, personal history measures such as age and race are used to further refine the analysis. Using such methods, it is possible to reallocate healthcare costs in cancer screening to patient subpopulations at increased cancer risk. It also permits identification of candidates for cancer prophylactic treatment.
申请公布号
WO2007150044(A2)
申请公布日期
2007.12.27
申请号
WO2007US71932
申请日期
2007.06.22
申请人
INTERGENETICS, INC.;OKLAHOMA MEDICAL RESEARCH FOUNDATION;RALPH, DAVID;ASTON, CHRISTOPHER;JUPE, ELDON