| 发明名称 |
COMPOUNDS FOR ENZYME INHIBITION |
| 摘要 |
One aspect of the invention relates to inhibitors that preferentially inh ibit immunoproteasome activity over constitutive proteasome activity. In cer tain embodiments, the invention relates to the treatment of immune related d iseases, comprising administering a compound of the invention. In certain em bodiments, the invention relates to the treatment of cancer, comprising admi nistering a compound of the invention. |
| 申请公布号 |
CA2657213(A1) |
申请公布日期 |
2007.12.27 |
| 申请号 |
CA20072657213 |
申请日期 |
2007.06.19 |
| 申请人 |
PROTEOLIX, INC. |
发明人 |
PARLATI, FRANCESCO;SHENK, KEVIN D.;BENNETT, MARK K.;ZHOU, HAN-JIE;LAIDIG, GUY J.;SMYTH, MARK S.;SYLVAIN, CATHERINE |
| 分类号 |
C07K5/068;A61K31/336;A61K31/404;A61K38/05;A61P35/00;A61P37/00;C07D303/32;C07D405/12;C07D409/12;C07K5/062;C07K5/065;C07K5/072;C07K5/078 |
主分类号 |
C07K5/068 |
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