Variants of human glycoprotein hormone alpha chain: compositions and uses thereof

摘要

The present invention provides human glycoprotein hormone (hGPH) alpha-chain splice variants, including isolated nucleic acids encoding these variants and the encoded amino acid sequences, as well as antibodies, antisense oligonucleotides, expression vectors and host cells comprising these sequences. The present invention further discloses the use of these sequences in the diagnosis, prevention and treatment of symptoms, diseases and disorders related to glycoprotein hormones.