CARBOXYLATED GLUCOSAMINE COMPOUNDS FOR INHIBITING THE ACTIVATION AND EXPRESSION OF MATRIX METALLOPROTEINASE-9 IN HUMAN FIBROSARCOMA CELLS AND MATRIX METALLOPROTEINASE-9 INHIBITORS CONTAINING THE SAME

摘要

The present invention relates to the CGIc compound for inhibiting the expression and activation of MMP-9 in HTl 080 and the MMP-9 inhibitor comprising the CGIc compound as an effective ingredient, which can inhibits the expression of AP-I in HtI 080 to effectively inhibit the expression and activation of MMP-9 such that it is effectuated in treating a wound, metastasis, rheumatoid arthritis, inflammation, hyperparathyroidism, diabetes, cornel ulcer, osteoporosis, stomach ulcer, trauma, pimple, burn, periodontal disease, arteriosclerosis or fracture.