发明名称 |
Chemically modified human growth hormone conjugates |
摘要 |
The present invention provides a chemically modified human Growth Hormone (hGH) prepared by binding a water soluble polymer to the protein. The chemically-modified protein according to the present invention may have a much longer lasting hGH activity than that of the unmodified hGH, enabling reduced dose and scheduling opportunities. |
申请公布号 |
ZA200403907(B) |
申请公布日期 |
2007.12.27 |
申请号 |
ZA20040003907 |
申请日期 |
2004.05.20 |
申请人 |
PHARMACIA CORPORATION |
发明人 |
FINN, RORY, F;LIAO, WEI;SIEGEL, NED, R. |
分类号 |
A61K38/27;A61K;A61K47/48;A61P5/06;A61P13/12;A61P15/00;C07K;C07K14/61;C07K17/08;C07K17/10 |
主分类号 |
A61K38/27 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|