发明名称 |
COMPOSITIONS AND METHODS FOR INHIBITING OPTIC NERVE DAMAGE |
摘要 |
Provided herein is a method of inhibiting optic nerve damage in an individual in need thereof, comprising administering to the individual an agent that inhibits peptidyl arginine deiminase 2 (PAD2). In a particular embodiment, the present invention is directed to a method of inhibiting glaucomatous optic nerve damage in an individual in need thereof, comprising administering to the individual an agent that inhibits peptidyl arginine deiminase 2 (PAD2). The present invention is also directed to a method of treating glaucoma {e.g., primary open angle glaucoma) in an individual in need thereof, comprising administering to the individual an agent that inhibits (e.g., specifically inhibits) peptidyl arginine deiminase 2 (PAD2). |
申请公布号 |
WO2007095250(A3) |
申请公布日期 |
2007.12.27 |
申请号 |
WO2007US03834 |
申请日期 |
2007.02.12 |
申请人 |
THE CLEVELAND CLINIC FOUNDATION;BHATTACHARYA, SANJOY, K.;CRABB, JOHN, W. |
发明人 |
BHATTACHARYA, SANJOY, K.;CRABB, JOHN, W. |
分类号 |
A61K31/00;A61K31/713;A61P27/00;C12N15/113 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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