发明名称 Optical probes for in vivo imaging
摘要 Disclosed is an image probing conjugate. The conjugate comprises a nanoparticle and a targeting agent. The nanoparticle comprises a dye which is encapsulated by a functionalized polymer, and the targeting agent is bound to the functional group of the polymer. The nanoparticle provides the conjugate with improved stability and an increased concentration of the dye. Therefore, the conjugate of the invention can be used for probing a small target which otherwise cannot be detected. Bonding the targeting agent to the nanoparticle allows precise image probing from the location where the targeting agent is placed.
申请公布号 US2007297988(A1) 申请公布日期 2007.12.27
申请号 US20070706734 申请日期 2007.02.15
申请人 WU BIN 发明人 WU BIN
分类号 A61K49/00;A61K9/66 主分类号 A61K49/00
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