发明名称 |
COMPOSITION AND METHODS FOR EXPRESSING REPORTER MOLECULES IN MAMMALIAN CELLS |
摘要 |
<p>Disclosed herein is a novel system and methods for expressing exogenous genes, such as genes encoding fluorescent proteins, in mammalian cells. In one embodiment of this system and methods, a gene essential for viral infectivity or replication in cell culture is deleted or inactivated in the genome of a non-mammaian DNA virus. The exogenous gene operably linked to a mammalian promoter is then inserted into the non-replicative non-mammalian DNA virus. The non-replicative virus is propagated in a host cell that expresses in trans the deleted or inactivated gene or a functional homolog.</p> |
申请公布号 |
WO2007149946(A2) |
申请公布日期 |
2007.12.27 |
申请号 |
WO2007US71704 |
申请日期 |
2007.06.20 |
申请人 |
INVITROGEN CORPORATION;HANSON, GEORGE;THOMPSON, DAVID |
发明人 |
HANSON, GEORGE;THOMPSON, DAVID |
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