НЕТАБЛЕТИРОВАННЫЕ ЖЕВАТЕЛЬНЫЕ ДОЗИРОВОЧНЫЕ ФОРМЫ ДЛЯ ИНДИВИДУАЛЬНОГО ВВЕДЕНИЯ

摘要

Non-tabletted, individually dosed administration forms comprising a composition of at least one pharmaceutically active substance dissolved or dispersed within a matrix material comprising a mixture of at least 0.2% by weight of a gelatine, at least one stabilising agent and at least one water-soluble alcohol and/or water as a solvent, which composition is plastic at elevated temperature, characterised in that: the stabilising agent is chosen from (i) esters of glycerine and fatty acids; (ii) products resulting from the alcoholysis/esterification reaction of such esters of glycerine and fatty acids with polyethylenglycols; in that the stabilising agent has a melting point in the range of 42° C. to 63° C.; and in that water is present in an amount not greater than 46% by weight of the composition.