| 摘要 |
PROBLEM TO BE SOLVED: To enhance the immune reconstitution of an HIV-infected patient, and hence treat HIV-associated oppotunistic symptoms caused by the immunocompromised state of the HIV patient. SOLUTION: This use of a CCR5 antagonist in the HIV-infected patient is to enhance the immune reconstitution of the patient for treating the HIV-associated oppotunistic symptoms caused by the immunocompromised state of the HIV patient. Since the patient having a CXCR4-using viral population obtains an advantage by the increase of the number of CD4 and/or CD8 cells, it becomes possible to treat such the patient by using the CCR5 antagonist. COPYRIGHT: (C)2008,JPO&INPIT
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