发明名称 |
VEGF antagonist formulations suitable for intravitreal administration |
摘要 |
Ophthalmic formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided suitable for intravitreal administration to the eye. The ophthalmic formulations include a stable liquid formulation and a lyophilizable formulation. Preferably, the protein antagonist has the amino acid sequence showing in SEQ ID No: 4 or amino acids 27-457 of SEQ ID No: 4. |
申请公布号 |
AU2007261536(A1) |
申请公布日期 |
2007.12.27 |
申请号 |
AU20070261536 |
申请日期 |
2007.06.14 |
申请人 |
REGENERON PHARMACEUTICALS, INC. |
发明人 |
ERIC FURFINE;DANIEL DIX;KENNETH S. GRAHAM;KELLY FRYE |
分类号 |
A61K9/00;A61K9/19;A61K38/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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