| 摘要 |
Disclosure is a method for the treatment of atherosclerosis by administering a pharmacological substance, namely a biliary compound with emulsifying properties, such as biliary salt or acid or precursor or derivative, into the systemic circulation via a variety of routes, including transdermal patch, sublingual preparation, catheter and oral ingestion. The pharmacological substance of biliary compounds also have the capability of crossing the fibrous cap of the atherosclerotic plaque to reach, emulsify and dissolve the cholesterol aggregates and in general the lipidic core within the plaque, so that the plaque is no longer vulnerable to rupture and arterial flow is restituted to physiological pre-plaque formation values. |
