CYCLIC AMINE COMPOUND

摘要

Disclosed is an excellent drug for treatment of hypertension. Specifically disclosed is a pharmaceutical agent containing a compound represented by the general formula (I) below or the like. [In the formula, R<SUP>1</SUP> represents H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted cyclic hydrocarbon, an optionally substituted heterocyclyl or the like; R<SUP>2</SUP> represents H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted cycloalkyl or the like; R<SUP>3</SUP> and R<SUP>4</SUP> independently represent H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted cycloalkyl or the like; R<SUP>5</SUP> and R<SUP>6</SUP> independently represent H, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted alkoxy or the like; R<SUP>7</SUP> and R<SUP>8</SUP> independently represent H, an optionally substituted alkyl, an optionally substituted cycloalkyl or the like; X represents a group represented by the above formula (II) or the like; A represents an optionally substituted cyclic hydrocarbon, an optionally substituted heterocyclyl or the like; Y represents a single bond, an optionally substituted alkylene, an optionally substituted alkenylene, -(CH<SUB>2</SUB>)<SUB>a</SUB>-X<SUP>1</SUP>-(CH<SUB>2</SUB>)<SUB>b</SUB>- (wherein X<SUP>1</SUP> represents -NH-, -O- or the like, and a and b respectively represent a number of 0-5) or the like; and B represents an optionally substituted cyclic hydrocarbon, an optionally substituted heterocyclyl or the like.]