TUMOR-TARGETING MONOCLONAL ANTIBODIES TO FZD10 AND USES THEREOF
摘要
<p>The present invention relates to an antibody or a fragment thereof which is capable of binding to a Frizzled homologue 10 (FZD10) protein, such as a mouse monoclonal antibody, a chimeric antibody and a humanized antibody. Also, the present invention relates to a method for treating and/or preventing FZD10-associated disease; a method for diagnosis or prognosis of FZD10-associated disease; and a method for in vivo imaging of FZD10 in a subject.</p>
申请公布号
WO2007148417(A1)
申请公布日期
2007.12.27
申请号
WO2006JP317155
申请日期
2006.08.24
申请人
ONCOTHERAPY SCIENCE, INC.;THE UNIVERSITY OF TOKYO;NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY;NAKAMURA, YUSUKE;KATAGIRI, TOYOMASA;NAKATSURU, SHUICHI;ENDO, KEIGO