POLYMER COATINGS CONTAINING DRUG POWDER OF CONTROLLED MORPHOLOGY
摘要
A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.
申请公布号
WO2007011707(A3)
申请公布日期
2007.12.27
申请号
WO2006US27321
申请日期
2006.07.14
申请人
MICELL TECHNOLOGIES, INC.;TAYLOR, DOUG;MCCLAIN, JIM;SMOKE, CLINT;COLE, MIKE;DEYOUNG, JAMES
发明人
TAYLOR, DOUG;MCCLAIN, JIM;SMOKE, CLINT;COLE, MIKE;DEYOUNG, JAMES