发明名称 PREPARATION COMPRISING MICROPARTICLES OF COMPLEX COMPOSED OF NUCLEIC ACID MOLECULE AND COLLAGEN
摘要 The present invention relates an additive comprising at least one substance selected from arginine, trometamol, meglumine, lysine, histidine, monoethanolamine, diethanolamine, triethanolamine, succinic acid, citric acid, tartaric acid, lactic acid, and salts thereof, which is useful in the prevention of aggregation of fine particulate complexes of a nucleic acid and collagen, and the production of a preparation comprising particulate complexes of controlled size which is suited for transporting a nucleic acid into cells.
申请公布号 EP1870110(A1) 申请公布日期 2007.12.26
申请号 EP20060729793 申请日期 2006.03.23
申请人 DAINIPPON SUMITOMO PHARMA CO., LTD.;KOKEN CO., LTD. 发明人 MAEDA, MIHO;KISHIMOTO, YOSHIKO
分类号 A61K48/00;A61K9/14;A61K9/16;A61K31/7088;A61K38/17;A61K47/12;A61K47/18;A61P17/00 主分类号 A61K48/00
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