| 摘要 |
<p>A biomarker is provided to be usefully used for monitoring and determining drugs or chemical materials having new nephrotoxicity and the danger of side effects, thereby being employed as a tool for investigating the action mode causing the nephrotoxicity. A biomarker for screening nephrotoxicity and side effect-inducing drugs comprises a gene selected from the group consisting of: Genebank XM_498383, Genebank AK001361, Genebank AJ002535, Genebank AK095253, Genebank AK026909, Genebank CR612719, Genebank NM_138417, Genebank CR601067, Genebank AK074052, Genebank XM_039495, Genebank BC067751, Genebank BM555452, Genebank AK025974, Genebank NM_152392, Genebank CR613579, Genebank NM_031298, Genebank BU673968, Genebank D67025, Genebank BC040191, Genebank XM_371569, Genebank NM_015946, Genebank BX537620, Genebank NM_005203, Genebank BC004102, Genebank AB075871, Genebank NM_005310, Genebank NM_173160, Genebank XM_499262, Genebank NM_080542, Genebank AY203954, Genebank NM_001005190, Genebank NM_005247, Genebank C033515, Genebank NM_000134, Genebank BC051890, Genebank Y008294, Genebank NM_014323, Genebank NM_001215, Genebank AY706204, Genebank NM_001004703, Genebank NM_002409, Genebank AK094580, Genebank NM_002918, Genebank AF097935, Genebank NM_012110, Genebank NM_001001524, Genebank BE889572, Genebank BX640959, Genebank AK122912, Genebank XM_495909, Genebank NM_020458, Genebank NM_145202, Genebank AF307451, Genebank AK024144, Genebank AB040955, Genebank AL833764, Genebank AY129013, Genebank AK096289, Genebank BM542003, Genebank AB018270, Genebank BC073828, Genebank AF279145, Genebank AY358993, Genebank BG167195, Genebank XM_498695, Genebank XM_373266, Genebank AK096265, Genebank XM_378608, Genebank AW575256, Genebank NM_001010867, Genebank AK023662, Genebank XM_290629, Genebank AL136662 and Genebank BC025741. The nephrotoxicity and side effect-inducing drug is selected from group consisting of amphotericin B, cisplatin and gentamicin.</p> |
