Angiogenesis is stimulated by introducing two replication-deficient adenovirus vectors to the endothelial cells or proximate to the endothelial cells of an organism. The first vector encodes VEGF-B167 or a fragment or conservative substitution thereof, the second vector encodes VEGF-A or VEGF-C, or fragments or conservative substitutions thereof.
申请公布号
EP1330252(A4)
申请公布日期
2007.12.26
申请号
EP20010992576
申请日期
2001.11.01
申请人
LUDWIG INSTITUTE FOR CANCER RESEARCH;AVENTIS PHARMA S.A.;LICENTIA LTD.