| 发明名称 |
Synthesis of 2-butyl-3-(1-trityl-1H-tetrazol-5-YL)biphenyl-4-YL)-1,3-diazaspiro[4,4]- non-ene-4-one |
| 摘要 |
Provided is a novel method of making 2-butyl-3-[[2'(1-trityl-1H-tetrazol-5-yl)biphen-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-ene-4-one, which can be converted to irbesartan. Also provided are methods of making irbesartan.
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| 申请公布号 |
US7312340(B2) |
申请公布日期 |
2007.12.25 |
| 申请号 |
US20060328966 |
申请日期 |
2006.01.09 |
| 申请人 |
TEVA PHARMACEUTICAL INDUSTRIES LTD. |
发明人 |
DOLITZKY BEN-ZION;KAFTANOV JULIA;PERTSIKOV BORIS;RUKHMAN IGOR;NISNEVICH GENNADY |
| 分类号 |
C07D257/00;C07D257/10;C07D403/10;C07D487/12 |
主分类号 |
C07D257/00 |
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