| 摘要 |
Claimed are a series of somatostatin agonists and uses thereof, according to formula (I), <?in-line-formulae description="In-line Formulae" end="lead"?>A<SUP>1</SUP>-cyclo[Cys-A<SUP>2</SUP>-D-Trp-A<SUP>3</SUP>-A<SUP>4</SUP>-Cys]-A<SUP>5</SUP>-Y<SUP>1</SUP>, (I)<?in-line-formulae description="In-line Formulae" end="tail"?> wherein A<SUP>1</SUP>, A<SUP>2</SUP>, A<SUP>3</SUP>, A<SUP>4</SUP>, A<SUP>5 </SUP>and Y<SUP>1 </SUP>are as defined in specification provided that the amine nitrogen of at least one peptide bond is substituted with a methyl group or pharmaceutically acceptable salts thereof.
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