发明名称 ADMINISTRATION OF ANTI-CD3 ANTIBODIES IN THE TREATMENT OF AUTOIMMUNE DISEASES
摘要 A method of treating an autoimmune disease, such as, diabetes or psoriasi s, by administering an anti-CD3 antibody, or anti-CD3 antibody fragment. The anti-CD3 antibody, or anti-CD3 antibody fragment, is administered over a co urse of treatment wherein, during the course of treatment, the anti-CD3 anti body, or anti-CD3 antibody fragment is administered in a total amount which does not exceed 300 .mu.g/kg when administered intravenously or, when admini stered other than intravenously, is administered in a total amount that does not exceed a total amount bioequivalent to 300.mu.g/kg of intravenous admin istration thereof.
申请公布号 CA2653387(A1) 申请公布日期 2007.12.21
申请号 CA20072653387 申请日期 2007.06.05
申请人 TOLERRX INC. 发明人 PONATH, PAUL;VAICKUS, LOUIS;ROSENZWEIG, MICHAEL
分类号 A61K39/395 主分类号 A61K39/395
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