发明名称 ACHE-NMDA COMBINATION WAFER
摘要 The invention relates to wafer-like pharmaceutical products based on hydr ophilic polymers, which rapidly disintegrate upon contact with humidity and which are used to treat dementia-related illnesses, wherein the presentation contains an active agent combination of at least two active agents suitable for the treatment of dementia (antidementia agents). Preferably, the antide mentia agents should be chosen from the group comprising acetyl cholinestera se inhibitors (AChE inhibitors) and NMDA antagonists (n-methyl-D-asparaginic acid antagonists). The invention further relates to the use of such an acti ve agent combination for the production of an orally administrable pharmaceu tical product for the treatment of dementia-related illnesses such as Alzhei mer's disease, as well as to a procedure for the symptomatic treatment of Al zheimer's disease by means of the oral administration of one of the above ph armaceutical products.
申请公布号 CA2653030(A1) 申请公布日期 2007.12.21
申请号 CA20072653030 申请日期 2007.06.04
申请人 LTS LOHMANN THERAPIE-SYSTEME AG 发明人 HOFFMANN, HANS-RAINER;THEOBALD, FRANK;BRANDLI, RETO
分类号 A61K9/00;A61K31/13;A61K31/27;A61K31/34;A61K31/4015;A61K31/505;A61K31/55;A61K45/06;A61P25/28 主分类号 A61K9/00
代理机构 代理人
主权项
地址