<p>The present invention provides a synthetic LDL nanoparticle comprising a lipid moiety and a synthetic chimeric peptide so s to be capable of binding the LDL receptor. The synthetic LDL nanoparticle of the present invention is capable of c incorporating and targeting therapeutics for diseases associated with the expression of the LDL receptor. The invention further provides methods of using such synthetic LDL nanoparticles.</p>
申请公布号
WO2007145659(A1)
申请公布日期
2007.12.21
申请号
WO2006US44163
申请日期
2006.11.13
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;CHILDREN'S HOSPITAL OAKLAND RESEARCH INSTITUTE;FORTE, TRUDY, M.;NIKANJAM, MINA