摘要 |
The present invention is in the field of pharmacotherapy of cognitive def icits in learning and memory by administering an .alpha.-aminoamide, particu larly safinamide. Examples of disturbances in cognition that can be treated with compounds of the invention are the ones associated with disorders such as autism, dyslexia, attention deficit hyperactivity disorder, schizophrenia , obsessive compulsive disorders, psychosis, bipolar disorders, depression, Tourette's syndrome, Mild Cognitive Impairment (MCI) and disorders of learni ng in children, adolescents and adults, Age Associated Memory Impairment, Ag e Associated Cognitive Decline, Alzheimer's Disease, Parkinson's Disease, Do wn's Syndrome, traumatic brain injury Huntington's Disease, Progressive Supr anuclear Palsy (PSP), HIV, stroke, vascular diseases, Pick's or Creutzfeldt- Jacob diseases, multiple sclerosis (MS), other white matter disorders and dr ug-induced cognitive worsening.
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