发明名称 ACHE-NMDA COMBINATION WAFER
摘要 The invention relates to wafer-like pharmaceutical products based on hydrophilic polymers, which rapidly disintegrate upon contact with humidity and which are used to treat dementia-related illnesses, wherein the presentation contains an active agent combination of at least two active agents suitable for the treatment of dementia (antidementia agents). Preferably, the antidementia agents should be chosen from the group comprising acetyl cholinesterase inhibitors (AChE inhibitors) and NMDA antagonists (n-methyl-D-asparaginic acid antagonists). The invention further relates to the use of such an active agent combination for the production of an orally administrable pharmaceutical product for the treatment of dementia-related illnesses such as Alzheimer's disease, as well as to a procedure for the symptomatic treatment of Alzheimer's disease by means of the oral administration of one of the above pharmaceutical products.
申请公布号 WO2007144083(A2) 申请公布日期 2007.12.21
申请号 WO2007EP04951 申请日期 2007.06.04
申请人 LTS LOHMANN THERAPIE-SYSTEME AG;HOFFMANN, HANS-RAINER;BRAENDLI, RETO;THEOBALD, FRANK 发明人 HOFFMANN, HANS-RAINER;BRAENDLI, RETO;THEOBALD, FRANK
分类号 A61K9/00;A61K31/13;A61K31/27;A61K31/34;A61K31/4015;A61K31/505;A61K31/55;A61K45/06;A61P25/28 主分类号 A61K9/00
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