| 摘要 |
The present invention relates to 11-O-desmethylmacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and / or prophylaxis of cancer or B-cell malignancies. |
| 申请人 |
BIOTICA TECHNOLOGY LTD.;GAISSER, SABINE;MARTIN, CHRISTINE;ZHANG, MING;WILKINSON, BARRIE;SHEEHAN, LESLEY;COATES, NIGEL;NUR-E-ALAM, MOHAMMED;VOUSDEN, WILLIAM;GAITATZIS, NIKOLAOS |
发明人 |
GAISSER, SABINE;MARTIN, CHRISTINE;ZHANG, MING;WILKINSON, BARRIE;SHEEHAN, LESLEY;COATES, NIGEL;NUR-E-ALAM, MOHAMMED;VOUSDEN, WILLIAM;GAITATZIS, NIKOLAOS |
