发明名称 Water soluble micelle-forming and biodegradable cyclotriphosphazene-taxol conjugate anticancer agent and preparation method thereof
摘要 A water-soluble micelle-forming cyclotriphosphazene-taxol conjugate anticancer agent, which is biodegradable, and thus, slowly release taxol, represented by the following Formula 1: wherein R is selected from the group consisting of H, CH<SUB>3</SUB>, (CH<SUB>3</SUB>)<SUB>2</SUB>CH and (CH<SUB>3</SUB>)<SUB>2</SUB>CHCH<SUB>2</SUB>; each n is the number of ethylene oxide repeating unit of poly(ethylene glycol) selected from the integers of 7-12; and x is 1 or 2.
申请公布号 US2007292384(A1) 申请公布日期 2007.12.20
申请号 US20070818744 申请日期 2007.06.15
申请人 SOHN YOUN-SOO;JI DA-EUN;JUN YONG-JOO;LEE HWA-JEONG 发明人 SOHN YOUN-SOO;JI DA-EUN;JUN YONG-JOO;LEE HWA-JEONG
分类号 A61K31/78;C08G79/02 主分类号 A61K31/78
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