OVER-COATED CHEWING GUM FORMULATION

摘要

PROBLEM TO BE SOLVED: To provide an over-coated chewing gum formulation for delivering a medicament or agent to an individual.

SOLUTION: In this chewing gum formulation, the medicament or agent is present within a coating that surrounds a center comprising a gum base. By chewing a gum, the medicament or agent is released from the formulation. Continuing to chew the formulation creates pressure in a buccal cavity forcing the medicament or agent into the systemic system of the individual through the oral mucosa contained in the buccal cavity. This greatly enhances the absorption of a drug into the systemic system as well as the bioavailability of the drug in the system.

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