| 发明名称 |
Inhibitors of serine proteases, particular HCV NS3-NS4A protease |
| 摘要 |
The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds.
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| 申请公布号 |
US2007292933(A1) |
申请公布日期 |
2007.12.20 |
| 申请号 |
US20070880629 |
申请日期 |
2007.07.23 |
| 申请人 |
PITLIK JANOS;COTTRELL KEVIN M;FARMER LUC J;PERNI ROBERT B;COURTNEY LAWRENCE F;VAN DRIE JOHN H;MURCKO MARK A |
发明人 |
PITLIK JANOS;COTTRELL KEVIN M.;FARMER LUC J.;PERNI ROBERT B.;COURTNEY LAWRENCE F.;VAN DRIE JOHN H.;MURCKO MARK A. |
| 分类号 |
A61K31/40;C12N9/99;A61K31/415;A61K31/425;A61K31/44;A61K31/4965;A61K38/00;A61K38/04;A61L2/16;A61P1/16;A61P31/12;A61P31/14;A61P37/02;A61P43/00;C07D209/00;C07D209/42;C07D213/02;C07D241/00;C07D277/14;C07D401/12;C07D403/12;C07D405/12;C07D405/14;C07D417/12;C07D471/02;C07D471/04;C07K5/04;C07K5/06;C07K5/10;C07K7/02 |
主分类号 |
A61K31/40 |
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