发明名称 БИЦИКЛИЧЕСКИЕ ПИРАЗОЛОНОВЫЕ ИНГИБИТОРЫ ЦИТОКИНОВ
摘要 The present invention relates to 6,7-dihydro-5H-pyrazolo[1,2a]pyrazol-1-ones which inhibit the extracellular release of inflammatory cytokines, said cytokines responsible for one or more human or higher mammalian disease states. The present invention further relates to compositions comprising said 6,7-dihydro-5H-pyrazolo[1,2a]pyrazol-1-ones and methods for preventing, abating, or otherwise controlling enzymes which are understood to be the active components responsible for the herein described disease states.
申请公布号 RU2006114580(A) 申请公布日期 2007.12.20
申请号 RU20060114580 申请日期 2004.11.09
申请人 ДЗЕ ПРОКТЕР ЭНД ГЭМБЛ КОМПАНИ (US) 发明人 КЛАРК Майкл Филип (US);ЛАФЛИН Стивен Карл (US);ГОЛЕБИОВСКИ Адам (US);БРУГЕЛЬ Тодд Эндрю (US);САБАТ Марк (US)
分类号 C07D487/04;A61K31/506 主分类号 C07D487/04
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