METHOD AND DEVICE FOR THE SEPARATION OF BIOLOGICAL PARTICLES CONTAINED IN A LIQUID BY MEANS OF VERTICAL FILTRATION

摘要

The basic filtration zone has a surface area equal to the diameter of the disc, which is equal to or higher than 0.8 cm. The filter has calibrated pores with a size 5-25 mu m and a density of pores is 3x10 to 5x10 6> pores/cm 2>. The filtration is carried out by depression of 0.05-1 bar with an over pressure lower than 1 bar and a badge is adapted for analyzing the residues by locating the basic filtration zone, where the filters are incorporated into a single filtration module with a reservoir and sterilized/free from enzymes which digest DNA/RNA/proteins. Before filtering the liquid, a sample of liquid containing biological liquid/cell culture cells are prepared for pre enrichment in cells. The number of basic filtration zone has the ratio of the volume filtered and the surface of filtration is lower than 40ml/cm 2>. Independent claims are included for: (1) a modulate filtration; and (2) a block support.