发明名称 NEW PROCESS FOR THE PREPARATION OF N-(1,1-DIMETHYLETHYL)-4-[[5'-ETHOXY-4-CIS-[2-(4-MORFOLINO)ETHOXY]-2'-OXOSPIRO[CYCLOHEXAN-1,3'-[H]INDOL]-1'(2'H)-YL]-SULFONYL]-3-METHOXYBENZAMIDEAND ITS SALTS
摘要 The invention relates to a process for the preparation of a compound of formula (I) and the salts thereof by reacting the compound of formula (II) with the compound of formula (III), which comprises carrying out the reaction in dimethyl sulfoxide, at a temperature between 10 .degree.C and 40 .degree.C, preferably at room temperature and transforming the resulting base of formula (I), if desired, into its salt by a method known per se.
申请公布号 CA2378087(C) 申请公布日期 2007.12.18
申请号 CA20002378087 申请日期 2000.07.13
申请人 SANOFI-SYNTHELABO 发明人 NAGY, LAJOS;SANTANE CSUTOR, ANDREA;MAJLATH, CSILLA;HEJA, GERGELY;CSIKOS, EVA;SAROSI, PETER;SIMON, KALMAN;SZOMOR, TIBORNE;EROSNE TAKACSY, TUNDE POSA;SZVOBODA, GYORGYNE;HALASZ, JUDIT;HERMECZ, ISTVAN;GONCZI, CSABA
分类号 A61K31/5377;C07D209/96;A61P5/12;C07B61/00 主分类号 A61K31/5377
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