| 发明名称 |
A FACTOR VIII-POLYPEPTIDE WITH FACTOR VIII:C-ACTIVITY |
| 摘要 |
Factor VIII polypeptides having FVIII:C activity that contain modifications in the A3 and/or C1 and/or C2 domains of the sequence of the light chain of Factor VIII, characterized by the binding affinity to low density lipoprotein receptor protein, and methods for producing the same. |
| 申请公布号 |
PT1129186(E) |
申请公布日期 |
2007.12.07 |
| 申请号 |
PT19990953425T |
申请日期 |
1999.11.10 |
| 申请人 |
STICHTING SANQUIN BLOEDVOORZIENING |
发明人 |
HANS-PETER SCHWARZ;KOENRAAD MERTENS;PETRUS JOHANNES LENTING;PETER TURECEK;JAN AART VAN MOURIK;HANS PANNEKOEK;FRIEDRICH SCHEIFLINGER |
| 分类号 |
C12N15/12;A61K38/00;A61K38/37;C07K14/705;C07K14/755;C12P21/02 |
主分类号 |
C12N15/12 |
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