THERMOSTABLIZATION OF DNA POLYMERASE BY PROTEIN FOLDING PATHWAY FROM A HYPERTHERMOPHILE ARCHAEON, PYROCOCCUS FURIOSUS

摘要

The present invention relates to maintaining the activity and stability of enzymes and biologically active proteins at increased temperatures by contacting same with a combination of isolated passive and active chaperones from a hyperthermopilic Archaeon, wherein the chaperones may include heat shock proteins, prefoldin and/or chaperonin proteins.