发明名称 |
HUMANIZED ANTI-HUMAN OSTEOPONTIN ANTIBODY |
摘要 |
It is intended to provide a humanized anti-human osteopontin antibody whi ch is superior to conventional anti-human osteopontin antibodies in terms of activities (an antigen-binding activity, a leukocyte migration inhibitory a ctivity and the like) and/or stability (resistance to heat, hypoxic conditio ns or denaturants, and the like).
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申请公布号 |
CA2653661(A1) |
申请公布日期 |
2007.12.06 |
申请号 |
CA20072653661 |
申请日期 |
2007.05.30 |
申请人 |
ASTELLAS PHARMA INC.;JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE |
发明人 |
TORIKAI, MASAHARU;NAKASHIMA, TOSHIHIRO;HIGUCHI, HIROFUMI;SAKAI, FUMIHIKO;YAMAMOTO, NOBUCHIKA |
分类号 |
C12N15/09;A61K39/395;A61P19/02;A61P29/00;A61P37/06;C07K16/18;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/08;G01N33/53 |
主分类号 |
C12N15/09 |
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