Methods for modulating apoptosis and neurite outgrowth in cells by modulating levels of PtdIns(4,5)P<SUB>2</SUB>. Agents for such modulation, including agents which inhibit or activate type I and type II PIP kinases, and methods for identifying such agents. Methods for treating or preventing hyperproliferative disorders and neurodegenerative diseases using such agents.
申请公布号
WO2007138334(A2)
申请公布日期
2007.12.06
申请号
WO2007GB02035
申请日期
2007.05.31
申请人
HET NEDERLANDS KANKER INSTITUUT;BISSET, LOUISE;HAMMONDS, TIM;DIVECHA, NULLIN;HALSTEAD, JONATHAN
发明人
BISSET, LOUISE;HAMMONDS, TIM;DIVECHA, NULLIN;HALSTEAD, JONATHAN
