发明名称 BI0L0GICAL PRODUCTS
摘要 There are disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human KDR. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases in which VEGF and/or KDR are implicated.
申请公布号 KR20070116110(A) 申请公布日期 2007.12.06
申请号 KR20077023689 申请日期 2007.10.16
申请人 CELLTECH R&D LIMITED 发明人 POPPLEWELL ANDREW GEORGE;TICKLE SIMON PETER;ZINKEWICH PEOTTI KAREN;MORRISON ROBERT KENDALL
分类号 C07K16/00;C12N15/09;A61K39/395;A61K47/48;A61P17/00;A61P17/06;A61P19/02;A61P29/00;A61P35/00;A61P35/04;A61P37/00;C07K14/71;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/13;C12P21/02;C12P21/08 主分类号 C07K16/00
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